Acarbose acb clusters: isolation of other genes of acarbose biosynthesis and acarbose metabolism from Actinoplanes sp. SE 50/110 and its use

摘要

The invention concerns biosynthesis genes from the acarbose gene cluster from Actinoplanes sp. SE 50/110, their isolation from Actinoplanes sp. or from producers of pseudooligosaccharides, a process for isolating these biosynthesis genes, the proteins coded by said genes, the expression of the proteins in heterologous host strains, and the use of the acarbose biosynthesis genes for optimizing the process.