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In vitro - a method for forecasting the course of the disease of patients with mammary carcinoma and / or for the diagnosis of a mammary carcinoma

机译:体外-预测乳腺癌患者病程和/或诊断乳腺癌的方法

摘要

Especially nodal conditions and tumour size, histological type, degree of differentiation and receptor condition are used nowadays for the prognosis and further planning of patients with carcinoma of the breast. Emphasis is placed on evaluation of the condition of the axillary lymph node. Patients with a negative axillary lymph node condition generally receive no after-treatment, as their prognosis is better; yet 30 % of these patients suffer relapses. The method proposed by this invention should make it possible to determine the patient's risk of recividation. In accordance with the invention, the invention makes it possible to predict the further evolution of patients with carcinoma of the breast by means of a qualitative or quantitative determinatin of T1 protein and/or T1-mRNA is sample material taken from the patients.
机译:如今,尤其是淋巴结状况和肿瘤大小,组织学类型,分化程度和受体状况被用于乳腺癌患者的预后和进一步计划。重点放在评估腋窝淋巴结的状况。腋窝淋巴结阴性的患者一般都不会接受治疗,因为他们的预后更好。这些患者中有30%复发。本发明提出的方法应该使得可以确定患者的再次接受治疗的风险。根据本发明,本发明使得可以通过定性或定量确定T1蛋白和/或T1-mRNA是取自患者的样品材料来预测患有乳腺癌的患者的进一步进化。

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