using a 17 - 1a directed against the antigen monoclonal antibody for the production of a drug for the treatment of a gastrointestinal tumor

摘要

A murine monoclonal antibody which specifically binds to an epitope of 17-1A antigen (or of a mixture of at least two of such antibodies) is used for the manufacture of a medicament for treating gastrointestinal tumor (e.g. gastrointestinal adenocarcinoma, colorectal or pancreatic carcinoma) by the parenteral administration (e.g. by intravenous infusion) of multiple doses of at least 100 milligrams or more per dose for a total dose of 0.1-5 grams (e.g. 1-5 grams) of antibody. Novel murine monoclonal antibodies are also described.