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Expression of the binding subunit of the cholera toxin with the aid of foreign promoters and / or leader sequences
Expression of the binding subunit of the cholera toxin with the aid of foreign promoters and / or leader sequences
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机译:借助外源启动子和/或前导序列表达霍乱毒素结合亚基
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摘要
Procedures are described whereby with the aid of recombinant DNA methods the expression of the binding subunit protein of cholera toxin (CTB) or derivatives thereof including hybrid gene fusion proteins to CTB has been brought under control of a foreign (non-cholera toxin) promoter and/or the CTB protein or its derivatives is being synthesized with a foreign rather than the natural leader peptide to facilitate translocation across cell membranes.
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