The invention provides methods and compositions relating to human tata- binding protein associated factor 105 (hTAF.sub.II 105) and related nucleic acids. The proteins may be produced recombinantly from transformed host cells from the disclosed hTAF.sub.II 105 encoding nucleic acids or purified from human cells. The invention provides isolated hTAF.sub.II 105 hybridization probes and primers capable of specifically hybridizing with the disclosed hTAF.sub.II 105 gene, hTAF. sub.II 105-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
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机译：本发明提供了与人tata结合蛋白相关因子105（hTAF.sub.105）和相关核酸有关的方法和组合物。所述蛋白质可以从公开的hTAF II 105编码核酸的转化宿主细胞重组产生，或者从人细胞纯化。本发明提供了分离的hTAF II 105杂交探针和引物，其能够与公开的hTAF II 105基因hTAF特异性杂交。 sub.II 105特异性结合剂，例如特异性抗体，以及在诊断，治疗和生物制药工业中制备和使用本发明组合物的方法。
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