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Derivatives of nucleosides, processes for the production of these derivatives of nucleosides and specific polyclonal and monoclonal antibodies of these derivatives

机译:核苷衍生物,这些核苷衍生物的生产方法以及这些衍生物的特异性多克隆和单克隆抗体

摘要

The invention relates to derivatives of nucleosides, processes for the production of these derivatives of nucleosides, as well as specific polyclonal and monoclonal antibodies of the aforementioned derivatives. PPThese derivatives comply with the following chemical formula: ##STR1## in which n is equal to 1, R.sup.1 stands for H or a linear mono-, di- or tri-phosphoric acid, R.sup.2 stands for a hydroxyl group, alkyl group, aryl group, a protein containing a free amino site, an aminoalkyl polystyrene or a silica grafted with an alkyl amine chain and R.sup.3 represents a substituted base chosen from among uracil, thymine, cytosine, guanine or adenine.
机译:本发明涉及核苷的衍生物,生产这些核苷的衍生物的方法,以及上述衍生物的特异性多克隆和单克隆抗体。

这些衍生物符合以下化学式:其中n等于1,R 1代表H或线性单,二或三磷酸, R 2代表羟基,烷基,芳基,含有游离氨基位点的蛋白质,氨基烷基聚苯乙烯或接枝有烷基胺链的二氧化硅,R 3代表选自以下的取代的碱:尿嘧啶,胸腺嘧啶,胞嘧啶,鸟嘌呤或腺嘌呤。

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