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Use of certain complexed somatostatin peptides for the invivo imaging of somatostatin receptor-positive tumors and metastasis

机译:某些复杂的生长抑素肽在体内对生长抑素受体阳性肿瘤和转移瘤的成像中的用途

摘要

Somatostatin peptides bearing at least one chelating group for a detectable element, said chelating group being linked to an amino group of said peptide, and said amino group having no significant binding affinity for somatostatin receptors, in free or salt form, are complexed with a detectable element and are useful as a pharmaceutical, e.g. a radiopharmaceutical for in vivo imaging of somatostatin receptor positive tumors or for therapy.
机译:具有至少一个用于可检测元件的螯合基团的生长抑素肽,所述螯合基团与所述肽的氨基连接,并且所述氨基以游离或盐的形式对生长抑素受体没有明显的结合亲和力,并与可检测的复合物复合。元素,可用作药物,例如用于生长抑素受体阳性肿瘤的体内成像或治疗的放射性药物。

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