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Methionine sulfone and S-substituted cysteine sulfone derivatives as enzyme inhibitors
Methionine sulfone and S-substituted cysteine sulfone derivatives as enzyme inhibitors
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机译:蛋氨酸砜和S-取代的半胱氨酸砜衍生物作为酶抑制剂
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摘要
This invention relates to compounds which inhibit thrombin or factor Xa. The compounds contain an aldehyde functionality and a methionine sulfone or S-substituted cysteine sulfone residue. The compounds and their pharmaceutical compositions are useful for preventing thrombosis in mammals which are suspected of having a condition characterized by abnormal thrombosis.
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