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Recombinant systems for expression of cholera B-subunit with the aid of foreign promoters and/or leader peptides
Recombinant systems for expression of cholera B-subunit with the aid of foreign promoters and/or leader peptides
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机译:借助外源启动子和/或前导肽表达霍乱B亚基的重组系统
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摘要
Disclosed herein are procedures whereby with the aid of recombinant DNA methods, the expression of the binding subunit protein of cholera toxin (CTB) or derivatives thereof including hybrid gene fusion proteins to CTB has been brought under the control of a foreign (non- cholera toxin) promoter and/or the CTB protein or its derivatives being synthesized with a foreign rather than the natural leader peptide to facilitate translocation across cell membranes.
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