The medicine formulation which the growth hormone and at least 1 basic amino acid residues and includes the peptide which at least includes 1 acidic amino acid residues, is stabilized

摘要

A pharmaceutical formulation comprising a growth hormone and a peptide comprising at least one basic amino acid residue and at least one acid amino acid residue as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.