METHOD FOR SPOTTING PROBE ONTO SOLID PHASE, PROBE ARRAY AND ITS PRODUCTION, AND DETECTION OF TARGET MATERIAL USING THE SAME, AND SPECIFICATION OF STRUCTURE OF TARGET MATERIAL

摘要

PROBLEM TO BE SOLVED: To provide a method for spotting, in high density, a probe for detecting a target single-stranded nucleic acid, for determining base sequence, and so on, by supplying and attaching liquid which contains a probe which binds specifically to a target material onto solid phase surface by the ink jet method. SOLUTION: This method comprises supplying liquid which contains a probe (e.g. singlestranded nucleic acid probe) which is capable of specifically binding to a target material to a bubble jet head 105 which is a kind of ink jet head and has a mechanism which gives thermal energy to the liquid and exhausts it, followed by exhausting and attaching the liquid onto the surface of a solid phase 103 such as a transparent glass plate as a droplet 104 by the ink jet method. This method allows spotting of a probe onto a solid phase to produce a probe array useful for detection of a target single-stranded nucleic acid and specification of base sequence of a target single-stranded nucleic acid.