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The man sterile Y chromosome deletion detection with multiplex primer connection
The man sterile Y chromosome deletion detection with multiplex primer connection
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机译:多重引物连接的人不育Y染色体缺失检测
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摘要
The present disclosure describes a method for probing the integrity of a Y chromosome utilizing multiplex PCR reactions which amplify specific regions of the human Y chromosome which have been linked to normal fertility in human males. The method is capable of detecting deletion mutations within the Y chromosome which are predictive of human male infertility. A kit containing reagents needed to practice the method is also disclosed.
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