Quinoline derivatives and quinazoline derivatives inhibiting platelet derived growth factor receptor autophosphorylation and their pharmaceutical composition containing them

摘要

The present invention is described below:In Formula 1, R1 and R2 are individually h or C1-C4 alkyl or R1 and R2 form together an alkylene of C1-C3, X is O, s or CH2, W is ch or N, q is a substituted aryl or substituted heteroa A novel quinoline derivative and quinazoline derivative having inhibitory action of platelet derived growth factor receptor autophosphorylation expressed in Lille group, and quinolizoline derivatives, and their pharmacically acceptable salts, and pharmaceutical composition containing these compounds It relates to a method of treating diseases related to abnormal growth of cells such as substances and tumor growth.