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MEDICINE FOR PROTECTING ISCHEMIC MYOCARDIOPATHY

机译:预防缺血性心肌病的药物

摘要

PROBLEM TO BE SOLVED: To obtain an ishemic myocardiopathy-protecting medicine or an angina medicine having an excellent effect on the ischemic myocardiopathy protection by compounding a specific moranoline derivative as an active ingredient. ;SOLUTION: This ischemic myocardiopathy-protecting medicine contains a compound of formula (R is a 1-8C alkyl, a 9-18C aralkenyl which may be substituted; A is a 6-18C acyl) as an active ingredient. The compound of the formula includes N-propyl-6-O-hexanoylmoranoline N-(p-cyanocinnamy1)-6-O- hexanoylmoranoline, N-[3-bis(o-chlorophenyl)-2-propenyl]-6-O-octanoylmoranoline. The compound of the formula is preferably contained as such or in a carrier in an amount of 0.01-99.5%, and is administered at a daily dose of 0.1-10 g for an adult as the active ingredient.;COPYRIGHT: (C)1999,JPO
机译:解决的问题:通过配合特定的吗啉衍生物作为活性成分,获得对缺血性心肌病保护具有优异效果的保护缺血性心肌病的药物或心绞痛药物。 ;解决方案:该缺血性心肌病保护药物包含作为活性成分的式(R为1-8C烷基,可被取代的9-18C芳烯基; A为6-18C酰基)的化合物。该式的化合物包括N-丙基-6-O-己酰基吗啉N-(对氰基肉桂基)-6-O-己酰基吗啉,N- [3-双(邻氯苯基)-2-丙烯基] -6-O-辛酰基吗啉。式中的化合物优选本身或在载体中的含量为0.01-99.5%,成人的日剂量为0.1-10 g作为有效成分。;版权:(C)1999 ,日本特许厅

著录项

  • 公开/公告号JPH1135465A

    专利类型

  • 公开/公告日1999-02-09

    原文格式PDF

  • 申请/专利权人 NIPPON SHINYAKU CO LTD;

    申请/专利号JP19970189750

  • 发明设计人 KOJIMA MASAHIKO;FUJITA MASAO;OCHI MASASHI;

    申请日1997-07-15

  • 分类号A61K31/445;A61K31/445;

  • 国家 JP

  • 入库时间 2022-08-22 02:32:02

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