PROBLEM TO BE SOLVED: To obtain an amphipathic polymer capable of forming micelles in water by converting part of the amino groups of a polymer having specified aminated repeating units into hydrophilic substituted amino groups and part thereof into hydrophobic substituted amino groups. ;SOLUTION: A polymer is produced which has repeating structural units represented by formula I (wherein R1 is lower alkylene; and m is 0 or 1) and has a number-average degree (n) of polymerization of 100 to 1,000. Part of the amino groups of this polymer are converted into hydrophilic substituted amino groups represented by formula II (wherein X is a hydrophilic group; R2 is lower alkylene; and p stands for a number-average degree of polymerization and is 15 to 100), and part thereof are converted into hydrophobic substituted amino groups represented by formula III (wherein R3 is a 6C or higher aliphatic hydrocarbon group), thus giving an amphipathic polymer capable of forming micelles in water. The obtained polymer can control by external stimulation the surface polarity of the micelle formed in water and is therefore useful as a means for extracting membrane proteins.;COPYRIGHT: (C)1997,JPO
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