首页> 外国专利> From the human serum albumen of gene manipulation origin is obtained the high purity human serum albumen content constituent

From the human serum albumen of gene manipulation origin is obtained the high purity human serum albumen content constituent

机译:从基因操纵来源的人血清白蛋白中获得高纯度人血清白蛋白含量的成分

摘要

PROBLEM TO BE SOLVED: To obtain an inexpensive human serum albumin preparation, capable of stably feeding collecting source, free from danger of mixing of virus, etc., and suitable for medical uses by purifying human serum albumin derived from generic engineering by combination of specific steps. ;SOLUTION: This human serum albumin-containing composition is obtained purifying human serum albumin derived from generic engineering and contains no producing host-related ingredients or other impurity ingredients and sufficiently suppressed in coloring. The composition is preferably obtained by carrying out ultrafiltration, heat treatment and acid treatment of cultured supernatant of a host producing human serum albumin and carrying out ultrafiltration of the treated material and subjecting the treated material to each treatment due to cation exchanger, hydrophobic chromatography, anionic exchanger, salting out, etc.;COPYRIGHT: (C)1997,JPO
机译:解决的问题:获得廉价的人血清白蛋白制剂,能够稳定地收集收集来源,没有病毒混合等的危险,并且通过结合特定的成分纯化源自通用工程的人血清白蛋白,从而适合医疗用途。脚步。 ;解决方案:该含人血清白蛋白的组合物是通过纯化衍生自通用工程的人血清白蛋白而获得的,并且不包含与宿主相关的生产成分或其他杂质成分,并且显着抑制了着色。所述组合物优选通过对产生人血清白蛋白的宿主的培养上清液进行超滤,热处理和酸处理,并对处理过的材料进行超滤,然后对处理过的材料进行阳离子交换,疏水色谱,阴离子处理等而得到。交换器,盐析等;版权所有:(C)1997,日本特许厅

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