A 1,25-dihydroxyvitamin D2 related compound and pharmaceutical composition having a calcium metabolism-regulating action containing such a compound.

摘要

Novel derivatives of vitamin D2 and more specifically 1alpha,25-dihydroxylated compounds of the vitamin D series. A process for the preparation of such derivatives is also provided as are certain intermediates in such process. The invention provides 1alpha,25-dihydroxyvitamin D2 derivatives and acylates thereof, which find ready application as substitutes for vitamin D3 or D2 or various of the known vitamin metabolites of these vitamins in their various applications to the correction of disorders involving calcium metabolism and associated bone disease.