NOVEL DERIVATIVES OF (1-HETEROAZOLYTLO-1-HETEROCYCLO)ALKANES AND THEIR APPLICATION AS AGENTS PROTECTING NERVE CELLS

摘要

PCT No. PCT/SE94/00663 Sec. 371 Date Mar. 6, 1995 Sec. 102(e) Date Mar. 6, 1995 PCT Filed Jul. 5, 1994 PCT Pub. No. WO93/13083 PCT Pub. Date Jul. 8, 1993This invention provides heterocyclic compounds of formula (I) that are potentially useful in the treatment of neuropsychiatric disorders associated with progressive processes leading to neuronal necrosis and dysfunction. In particular, the novel compounds which do not bind to muscarinic receptors are inhibitors of delayed neuronal death as shown in the gerbil bilateral occlusion model of ischemia.