首页> 外国专利> Process for the preparation of a pharmaceutical composition for the administration of micro capsules with a protein or a polypeptide deliverance controlled by integration with a polymeric hidrofobicoBiodegradavel

Process for the preparation of a pharmaceutical composition for the administration of micro capsules with a protein or a polypeptide deliverance controlled by integration with a polymeric hidrofobicoBiodegradavel

机译:制备用于给药微胶囊的药物组合物的方法,该微胶囊具有通过与聚合物hidrofobicoBiodegradavel整合而控制的蛋白质或多肽递送

摘要

A drug delivery system for controlled release of a protein or polypeptide comprising a hydrophobic biodegradable polymer and a protein or polypeptide. A physical interaction is present between the polymer and the protein or polypeptide, thus, allowing protection and controlled release of the protein or polypeptide in-vivo. The drug delivery system may be prepared by a polymer precipitation technique or a microsphere technique.
机译:一种用于控制释放蛋白质或多肽的药物递送系统,其包含疏水性可生物降解的聚合物和蛋白质或多肽。聚合物与蛋白质或多肽之间存在物理相互作用,因此可以在体内保护和控制释放蛋白质或多肽。药物输送系统可以通过聚合物沉淀技术或微球技术制备。

著录项

  • 公开/公告号PT98397B

    专利类型

  • 公开/公告日1999-01-29

    原文格式PDF

  • 申请/专利权人 UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION;

    申请/专利号PT19910098397

  • 发明设计人 PATRICK P. DELUCA;

    申请日1991-07-19

  • 分类号A61K9/52;A61K9/16;A61K38/00;

  • 国家 PT

  • 入库时间 2022-08-22 02:26:14

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