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EPIDERMIC HUMAN GROWTH FACTOR (HEGF) PREPARATION PROCESS OF ITS CONGENERERS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
EPIDERMIC HUMAN GROWTH FACTOR (HEGF) PREPARATION PROCESS OF ITS CONGENERERS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
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机译:流行性感冒人类生长因子(HEGF)的制备过程及其所含药物成分
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摘要
The invention in growth factor compositions includes: a novel compound which is a separate pure nicked or pure non-nicked species of epidermal growth factor EGF1-48 or its hEGF1-47 or hEGF1-49 congener compound, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition in dosage form comprising an effective amount of the novel compound; and use thereof for treating abnormal cell growth conditions including gastrointestinal/duodenal lesions; and methods of making the pure hEGF species. This unique therapeutic utility is enhanced by the unexpected and heretofore unappreciated structural stability and resistance of the pure species to enzymatic degradation.
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