首页> 外国专利> An Acid Addition Salt of a 10 - aminoalifatil - dibenz B, F, oxepina, Employment, production method thereof, a 10 - aminoalifatil - dibenz B, F oxepina,A Pharmaceutical Preparation containing such Salt or the oxepina and Procedure for the treatment of diseases neurodegenerativ

An Acid Addition Salt of a 10 - aminoalifatil - dibenz B, F, oxepina, Employment, production method thereof, a 10 - aminoalifatil - dibenz B, F oxepina,A Pharmaceutical Preparation containing such Salt or the oxepina and Procedure for the treatment of diseases neurodegenerativ

机译:10-氨基阿法替丁-苯甲酸酯[B,F],氧杂环丁酸的酸加成盐,其制备方法,10-氨基阿法替丁-苯甲酸酯[B,F]-氧杂环丁烷,含有该盐或氧杂环丁菌的药物制剂及其制备方法神经变性疾病的治疗

摘要

Refers to Addition salts with acids of - 10 - aminoalifatil dibenz [B, F] oxepina of formula (i), in which ALK is a Bivalent radical aliphatic amino Group, res a insubstituido,Monosubstituido or disubstituido radical aliphatic and / or aralifu00e1ticos monovalent or divalent or disubstituido by radicalesalifu00e1ticos aralifu00e1ticos and R1, R2,R3 and R4 independently among them denote Hydrogen, Lower alkyl, Lower alkoxy, halogen otrifluorometilo with Organic carboxylic acids.These salts can be used as active substances antineurodegenerativas for Medicines.It also relates to the novel compounds of formula (i) in its free form, the use of said salts, a process for producing.Apreparaciones Pharmaceutical containing such salts or compounds of formula (i) in its free form and Procedure for the treatment of Neurodegenerative Diseases using such saltsCompounds of formula (i) in free form.
机译:指具有式(i)的-10-氨基alifatil dibenz [B,F]氧杂环丁烷酸的加成盐,其中ALK是二价自由基脂族氨基,是脂族的取代基,单取代或二取代基和//或aralif R 1,R 2,R 3和R 4各自独立地表示氢,低级烷基,低级烷氧基,卤素三氟金属基与有机羧酸的单价或二价或二取代基,其中的盐可用作活性类抗变色剂。药物。本发明还涉及其游离形式的式(i)的新型化合物,所述盐的用途,生产方法。含有这种盐或游离形式的式(i)的化合物的制脂剂及其制备方法使用此类盐的游离形式的式(i)化合物治疗神经退行性疾病。

著录项

  • 公开/公告号TR9802482T2

    专利类型

  • 公开/公告日1999-02-22

    原文格式PDF

  • 申请/专利权人 NOVARTIS AG;

    申请/专利号TR19980002482T

  • 申请日1997-05-28

  • 分类号C07D313/14;C07D405/06;

  • 国家 TR

  • 入库时间 2022-08-22 02:26:04

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