CLONING AND EXPRESSION OF A PROTEIN WHICH MODULATES CELLULAR RESPONSE TO TYPE I INTERFERON

摘要

The gene encoding a protein (L7) which appearsto be a part of the human Type I interferon receptor hasbeen cloned and expressed by recombinant DNA techniques.The protein imparts a non-species specific enhancedresponsiveness to Type I interferon to transformed cells.The protein is found on the surface of Daudi cells and hasstructural features characteristic of receptor proteins.