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DOCUMENTATION MEANS FOR REPERTOIRES OF NKR IMMUNORECEPTORS AND/OR ACTIVATORY OR NON-INHIBITORY IMMUNORECEPTOR COUNTERPARTS OF NKR IMMUNORECEPTORS
DOCUMENTATION MEANS FOR REPERTOIRES OF NKR IMMUNORECEPTORS AND/OR ACTIVATORY OR NON-INHIBITORY IMMUNORECEPTOR COUNTERPARTS OF NKR IMMUNORECEPTORS
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机译:NKR免疫受体库和/或NKR免疫受体激活性或非抑制性免疫受体配伍的文献资料
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摘要
The invention relates to an in vitro method of documenting a repertoire of NKR immunoreceptor (s) and / or NKR counterparts, comprising (i) the use of at least one pair of 3 'and 5' oligonucleotides capable of to hybridize to an NKR target receptor, or NKR counterpart, and not to hybridize to a functional counterpart receptor for this target receptor; (ii) bringing this pair of 3 'and 5' oligonucleotides into contact with the DNA or cDNA of a sample to be studied; and (iii) the detection of the hybrids possibly formed. The invention also relates to the biological applications of this method, in particular screening of a bank of organs, tissues, cells with a view to transplants, and to kits for its implementation.
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