Orf, a substrate for extracellular signal-regulated kinase, erk-6, and related methods

摘要

The present invention relates to ORF polypeptide, nucleic acids encoding such polypeptide, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptide, assays utilizing such polypeptide, and methods relating to all of the foregoing. Methods for treatment, diagnosis, and screening are provided for ORF related diseases or conditions characterized by an abnormal interaction between an ORF polypeptide and an ORF binding partner.