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NUCLEIC ACID EXPRESSION CONSTRUCTS INCORPORATING A HETEROLOGOUS INTRON WHOSE NATURAL POSITION IS WITHIN THE 5'UNTRANSLATED REGION OF ITS GENE
NUCLEIC ACID EXPRESSION CONSTRUCTS INCORPORATING A HETEROLOGOUS INTRON WHOSE NATURAL POSITION IS WITHIN THE 5'UNTRANSLATED REGION OF ITS GENE
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机译:包含天然位点的杂种内含子的核酸表达构建体在其基因的5'非翻译区中
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摘要
A nucleic acid expression construct comprising: (a) a promoter; (b) an intron whose natural position is within the 5'-untranslated region of a gene from which it is derived; (c) a coding sequence; and (d) a 3'-flanking sequence wherein the intron (b) is not derived from the same gene as that from which either the promoter (a) or the protein-coding sequence (c) is derived and processes, vectors, hosts and uses involving such a construct to obtain inter alia an increase in the level of expression of the coding sequence.
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