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METHODS FOR PREVENTING AND TREATING FIBROTIC DISEASES RESULTING FROM ACCUMULATION OF EXCESS EXTRACELLULAR MATRIX INDUCED BY TGF beta USING RENIN INHIBITORS
METHODS FOR PREVENTING AND TREATING FIBROTIC DISEASES RESULTING FROM ACCUMULATION OF EXCESS EXTRACELLULAR MATRIX INDUCED BY TGF beta USING RENIN INHIBITORS
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机译:使用肾素抑制剂预防和治疗由TGF-β诱导的过量细胞外基质积聚导致的纤维化疾病
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摘要
The present invention is methods for inhibiting the renin-induced production of TGF beta using a renin inhibitory agent to reduce excess accumulation of extracellular matrix in tissue in a subject, and to the use of renin inhibitory agents and additional TGF beta inhibitory agents to reduce TGF beta production to treat and prevent fibrotic diseases.
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