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USE OF TOPOISOMERASE TO ENHANCE RT-BASED MOLECULAR BIOLOGY TECHNIQUES AND RT-BASED GENE DELIVERY
USE OF TOPOISOMERASE TO ENHANCE RT-BASED MOLECULAR BIOLOGY TECHNIQUES AND RT-BASED GENE DELIVERY
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机译:使用拓扑异构酶增强基于RT的分子生物学技术和基于RT的基因传递
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摘要
The present invention relates to the use of topo I and agents which enhance topo I activity to improve the efficiencies of retroviral-based gene therapies and reverse-transcriptase-based molecular biology techniques. In accordance with the present invention, topo I and agents which enhance topo I may be used to improve integration efficiencies of retroviral vectors and have utility in improving retroviral vector-based gene delivery and gene therapy techniques.
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