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Conversion of pyridinoline to deoxypyridinoline
Conversion of pyridinoline to deoxypyridinoline
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机译:吡啶啉转化为脱氧吡啶啉
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摘要
The present invention involves the synthetic conversion of pyridinoline (PYD) to deoxypyridinoline (DPD) via an intermediate ester which is subsequently cleaved. The transformation of PYD into a xanthate-type ester intermediate facilitates the subsequent removal of the substituted hydroxyl functionality thus providing the desired DPD. The method provides a new chemical pathway for the preparation of DPD, resulting in significantly increased yields as compared to traditional methods of product isolation.
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