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15,15-DIALKYL-SUBSTITUTED DERIVATIVES OF ESTRADIOL
15,15-DIALKYL-SUBSTITUTED DERIVATIVES OF ESTRADIOL
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机译:雌二醇的15,15-二烷基取代衍生物
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摘要
New 15,15-dialkyl-substituted derivatives of the estradiol of general formula I IMAGE (I) in which R1 and R2, independently of one another, are each a hydrogen atom or a straight-chain alkanoyl group with 1 to 10 carbon atoms, a branched-chain alkanoyl group with 3-10 carbon atoms, an alkanoyl group of 3-10 carbon atoms containing a cycloaliphatic structure of 3-6 carbon ring atoms or a benzoyl group, and R3 and R4, independently of one another, are each a straight-chain alkyl group with 1 to 10 carbon atoms or a branched-chain alkyl group with 3 to 10 carbon atoms, are described, a process for their production and initial products for this process. The new compounds have-also after oral administration-high estrogenic effectiveness and are suitable for the production of pharmaceutical agents.
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