HORMONE-MEDIATED METHODS FOR MODULATING EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS, AND PRODUCTS RELATED THERETO

摘要

According to the present invention, a variety of methods are provided, for modulating ecdysone receptor of the foreign gene of expression in mammalian subject using its modification. And additionally provide the ecdysone receptor of modification, and the nucleic acid with number and heterodimeric receptor and containing the ecdysone receptor for encoding modification of the invention, the moulting hormone response element of modification, gene transfer vector, recombinant cell and transgenic animals contain the ecdysone receptor of nucleic acid encode modification of the invention.