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Mouse monoclonal antibody against surface antigen free-S 1 of hepatitis B virus, hybridoma cell line producing the same, and method for producing the same
Mouse monoclonal antibody against surface antigen free-S 1 of hepatitis B virus, hybridoma cell line producing the same, and method for producing the same
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机译:抗乙型肝炎病毒表面抗原游离-S 1的小鼠单克隆抗体,产生该抗体的杂交瘤细胞系及其制备方法
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摘要
The present invention relates to a monoclonal antibody that binds to a surface antigen pre-S1 (pre-S1) of hepatitis B virus (HBV), a hybridoma cell line that produces the antibody, and a method of producing the same. Specifically, the present invention relates to a mouse monoclonal antibody specifically recognizing an epitope containing amino acids 43-49 of HBV surface antigen pre-S1, which can neutralize various subtypes and mutant HBV, thereby preventing HBV infection It can be widely used for treatment.
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