Oral immunization with yolk antibody for prevention and treatment of swine coli diarrhea

摘要

The present invention relates to an oral immunologic agent capable of effectively preventing and treating diarrhea caused by Escherichia coli showing a high incidence in young pigs. The immunologic agent according to the present invention is a test vaccine containing an attachment factor and dipytoxin of Escherichia coli. After inoculating the laying hens, the specific antibodies were extracted from the egg yolk of the immunized chicken eggs and formulated, and thus the immunologic preparations were used very safely because the yolk antibodies were extracted using food additives. It shows an excellent protective ability in the target animal, can be stored for a long time by the freeze-drying method, etc., there is an advantage that can be used by adjusting the concentration. E. coli can be prevented and treated by directly supplying high concentrations of antibodies to E. coli caused by the lack of colostrum antibody value, the lack of colostrum intake, and the loss of maternally transferred antibodies. It can reduce the problem of antibiotic treatment.