ORAL IMMUNOLOGICAL PREPARATION CONTAINING EGG-YOLK ANTIBODIES, FOR PREVENTION AND TREATMENT OF PORCINE DIARRHEA CAUSED BY ENTEROTOXIGENIC ESCHERICHIA COLI

摘要

PURPOSE: An oral type immunizing formulation is provided for efficiently protecting and treating diarrhea caused by porcine enteric colibacillosis frequently appeared over young porcine by preparing testing vaccine to form antibody by inoculating it to egg-laying chicken and using egg generated by the immunized chicken. CONSTITUTION: The oral type immunizing formulation includes the efficient protein component for holding the yolk of egg produced by a specific process comprising inoculating the test vaccine containing ciliate antigens K88, K99 and 987p and heat-labile toxin of intestines to the egg-laying chicken; diluting the yolk removed from the egg of the immunized chicken in phosphorous buffer solution; adding to the resulting diluted solution with the carrageenan compound to centrifuge the solution; and filtering the supernatant solution. The formulation is effective to protect and treat diarrhea caused by enteric colibacillosis often appeared over young pork.