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METABOLITES OF GINSENG SAPONINS BY HUMAN INTESTINAL BACTERIA AND ITS PREPARATION FOR AN ANTICANCER

机译:人肠细菌对人参皂苷的代谢及其抗癌药的制备

摘要

The present invention relates to a ginsenoside Mc which is an enterobacterial metabolite of ginseng saponin having the following structural formula and an anticancer agent containing the same as an active ingredient.;In addition to the novel compound, the present invention contains one of Compound K, Compound Y, or 20 (S) -protopanaxatriol, which is an enterobacterial metabolite of ginseng saponin, as an active ingredient and at least one pharmaceutically acceptable carrier. The agent of the present invention is useful as a new type of anticancer agent in which anticancer activity is expected by enhancing immunity and inhibiting tumor angiogenesis and cancer cell invasion.
机译:本发明涉及一种人参皂苷Mc,其是具有以下结构式的人参皂苷的肠细菌代谢产物和含有该人参皂苷的抗癌剂作为活性成分;除新颖化合物外,本发明还包含化合物K中的一种,作为有效成分和至少一种药学上可接受的载体的化合物Y或20(S)-原人参三醇是人参皂苷的肠细菌代谢产物。本发明的药剂可用作新型的抗癌剂,其中通过增强免疫力和抑制肿瘤血管生成和癌细胞侵袭来预期抗癌活性。

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