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Metabolites of ginseng saponins by human intestinal bacteria and its preparation for an anticancer

机译:人参皂苷被人肠道细菌代谢物及其抗癌药的制备

摘要

This invention relates to ginsenoside Mc with formula (I), ##STR1## an intestinal flora metabolite of ginseng saponin and anticancer agent containing it as an active ingredient. In addition to a novel compound, the anticancer agent of this invention consists of one active ingredient elected from compound K, compound Y or 20(S)- protopanaxatriol, intestinal flora metabolites of ginseng saponin, together with one or more pharmaceutically acceptable carriers. Said agent is a novel type of potential anticancer agent since it has immunopotentiating actions including inhibitory actions on the vascularization of tumors and extravasation of cancer cells.
机译:本发明涉及具有式(I)的人参皂苷Mc,人参皂苷的肠道菌群代谢产物和以其为有效成分的抗癌剂。除新型化合物外,本发明的抗癌药还包括选自化合物K,化合物Y或20(S)-原托那三醇,人参皂苷的肠道菌群代谢产物以及一种或多种药学上可接受的载体的活性成分。所述药物是新型的潜在抗癌药物,因为它具有免疫增强作用,包括对肿瘤血管形成的抑制作用和癌细胞的外渗。

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