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Conjugated terthiophene and furan compounds with photoenhanced biocidal properties

机译:具有光增强杀生物特性的共轭对噻吩和呋喃化合物

摘要

Conjugates of a carrier molecule and an organic molecule producing singlet oxygen after irradiation are useful in diagnostic and therapeutic applications. The organic molecule is a terthienyl or terfuranyl compound derivatized to react with amino, thiol, or saccharide groups of the carrier molecule. Suitable carrier molecules include antibodies, peptides, haptamers, sugars, and other analogous molecules which direct the organic molecule to a biological target.
机译:辐照后载体分子和有机分子产生单线态氧的缀合物可用于诊断和治疗应用。有机分子是被衍生化以与载体分子的氨基,硫醇或糖基反应的叔噻吩基或叔呋喃基化合物。合适的载体分子包括抗体,肽,半抗原,糖和将有机分子导向生物靶标的其他类似分子。

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