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Method of screening for inhibitors of human thyrotropin releasing hormone (TRH) receptor

机译:筛选人类促甲状腺激素释放激素(TRH)受体抑制剂的方法

摘要

A human receptor protein capable of binding TRH, a DNA coding for said protein, use of the proetein and DNA, a method for preparing said protein, and antibodies to the protein are described.P PThe human TRH receptor protein and the DNA coding for the protein of the present invention are useful as (1) a diagnostic composition for neuropathy (particularly, dementia), (2) a pharmaceutical composition for neuropathy and (3) a material used for screening a TRH receptor agonist or antagonist.
机译:描述了能够结合TRH的人受体蛋白,编码所述蛋白的DNA,蛋白和DNA的用途,制备所述蛋白的方法以及对该蛋白的抗体。编码本发明蛋白的DNA可用作(1)神经病(特别是痴呆)的诊断组合物,(2)神经病的药物组合物和(3)用于筛选TRH受体激动剂或拮抗剂的材料。

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