Chiral pyridylphosphines and their application in asymmetric catalytic hydrogenation of 2-arylpropenoic acids

摘要

It is novel, the formula of photolytic activity phosphorus compound, ##STR1## wherein R. Use dinner. The alkyl of the chain of 1 expression hydrogen atom, straight chain or branching has 1 to 6 carbon atom, Rsup.2 represent hydrogen atom, halogen atom, low alkyl group (1 to 6 carbon atom), lower alkoxy, (1 to 6 carbon atom), hydroxyl, chiral hydroxyalkyl and amino (1& deg; 2° 3° ) vinyl or allyl and R. Use dinner. 3 indicate phenyl, aryl, and cyclohexyl, replaces and unsubstituted cycloalkyl group, hetero-aromatic ring describe. The formula compound is converted into high value aryl -2- acid as the asymmetric 2- arylpropenoic acid leads that the ruthenium complex of highly useful ligand effectively prepare catalyst.