Polypeptides and methods for the detection of L. tropica infection

摘要

Compounds and methods for diagnosing Leishmania tropica infection, or for screening for L. tropica infection, are disclosed. The disclosed compounds are polypeptides that contain one or more epitopes of an L. tropica protein, Lt-210. The compounds are useful in a variety of in vitro and in vivo immunoassays for detecting L. tropica infection. The polypeptides are further useful in vaccines and pharmaceutical compositions for preventing leishmaniasis in individuals exposed to L. tropica.