Hormone-mediated methods for regulating expression of foreign genes in mammalian systems, products associated with it

摘要

(57) SUMMARY The present invention, various methods for modulating by using a modified ecdysone receptor, the expression of foreign genes in a mammalian subject is provided. Modification and ecdysone receptor, a heterodimer receptor and homomeric containing the same modified ecdysone receptor, a nucleic acid encoding a modified ecdysone receptor of the present invention, code modification and ecdysone response element, a modified ecdysone receptor of the present invention a gene transfer vector containing a nucleic acid which, recombinant cells, and transgenic animals are also provided.