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Iron Complexes with Nitrogen-Containing Macrocycle Ligands Effective as Catalysts for Dismutatin Superoxide
Iron Complexes with Nitrogen-Containing Macrocycle Ligands Effective as Catalysts for Dismutatin Superoxide
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机译:含氮大环配体的铁配合物可有效催化二歧蛋白超氧化物歧化酶
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摘要
Pharmaceutical compositions of low molecular weight mimics of superoxide dismutase (SOD) represented by formula (I), wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, and R'9, and X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, ischemic/reperfusion injury, stroke, atherosclerosis, inflammatory bowel disease and all other conditions of oxidant-induced tissue damage or injury.
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