Pyrazolidine derivative and radical scavenger, cerebral infarction inhibitor, cerebral edema inhibitor

摘要

A pyrazolidine derivative or a salt thereof in accordance with the present invention is expressed by the following formula 1: CHEM wherein A represents a group expressed by - CH2-, -CO-, -CS-, -CH2CO-, or -CH=CH-CO-; B represents a group expressed by -O- or -NH-; n is an integer of 1 or 2; R represents an alkenyl group; and R1 and R2 represent a lower alkyl or benzyl group. The pyrazolidine derivative above mentioned, as a radical scavenger, has antioxidant effect and lipid peroxidation inhibitory activity so as to be available for inhibiting brain infarction or brain edema.