TREATMENT FOR IMPOTENCE DERIVED FROM DAMAGE OF SPINAL MARROW

摘要

PROBLEM TO BE SOLVED: To provide a method for treatment of impotence by dosing an animal having a damaged spinal marrow with a specific compound. SOLUTION: This method comprises dosing an animal having a damaged spinal marrow with a compound of formula I (R1 is 1-3C alkyl or the like; R2 is H, a 3-6C cycloalkyl or the like; R3 is a 3-6C alkenyl or the like; and R4 is OH, CN or the like), pref. sildenafil 5-[2-ethoxy-5-(4-methyl-1- piperazinylsulfonyl)-phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazo lo[4,3- d]pyrimidin-7-one} of formula II or a compound of formula III. The dose is 10 to 200 mg of the compound of formula I, if necessary, one time or less a day by oral administration.