首页> 外国专利> MONOCLONAL ANTIBODY TO BE SPECIFICALLY REACTED WITH COPLANAR PCB SUBSTANTIALLY NOT REDUCING ANTIGEN RECOGNITION CHARACTERISTIC EVEN IN 50 (V/V) AQUEOUS SOLUTION OF ORGANIC SOLVENT, AND ITS MEASUREMENT

MONOCLONAL ANTIBODY TO BE SPECIFICALLY REACTED WITH COPLANAR PCB SUBSTANTIALLY NOT REDUCING ANTIGEN RECOGNITION CHARACTERISTIC EVEN IN 50 (V/V) AQUEOUS SOLUTION OF ORGANIC SOLVENT, AND ITS MEASUREMENT

机译:需与共平面PCB进行特定反应的单克隆抗体基本上不会降低50%(V / V)%的有机溶剂水溶液的抗原识别特性及其测量

摘要

PROBLEM TO BE SOLVED: To obtain a monoclonal antibody capable of omitting the pretreatment of extraction with an organic solvent and analyzing a coplanar PCB simply quickly in high accuracy by making the antigen recognition characteristics not lowered even in an aqueous solution of an organic solvent having a fixed concentration. ;SOLUTION: This monoclonal antibody recognizes a coplanar PCB such as 3,3,3'4'-tetrachlorobiphenyl (PCB-#77), 3,4,5,3',4'-pentachlorobiphenyl (PCB-#126) or 3,4,5,3'4',5'-hexachlorobiphenyl (PCB-#169) and will not be substantially lowered in antigen recognition characteristics even in 50 (v/v)% aqueous solution of an organic solvent. A coplanar PCB existing in an aqueous solution of an organic solvent or a buffer solution not containing an organic solvent is brought into contact with the monoclonal antibody to form an antigen-antibody complex and the amount of the antigen-antibody complex formed is measured to measure the coplanar PCB.;COPYRIGHT: (C)2000,JPO
机译:要解决的问题:通过获得即使在具有有机溶剂的有机溶剂的水溶液中也不会降低抗原识别特性,从而能够快速,高精度地省去有机溶剂提取的预处理和共面PCB的单克隆抗体。固定浓度。 ;解决方案:该单克隆抗体可识别共面的PCB,例如3,3,3'4'-四氯联苯(PCB-#77),3,4,5,3',4'-五氯联苯(PCB-#126)或3 ,4,5,3'4',5'-六氯联苯(PCB-#169),即使在50(v / v)%的有机溶剂水溶液中,其抗原识别特性也不会显着降低。使存在于有机溶剂的水溶液或不含有机溶剂的缓冲溶液中的共面PCB与单克隆抗体接触以形成抗原-抗体复合物,并测量形成的抗原-抗体复合物的量以测量共面印刷电路板;;版权:(C)2000,JPO

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