NOVEL MONOCLONAL ANTIBODY AND IMMUNOLOGICAL ANALYSIS OF NICK amp;beta;2 GLYCOPROTEIN I

摘要

PROBLEM TO BE SOLVED: To provide an immunological analysis, capable of rapidly and accurately measuring nick β2 glycoprotein I in a living body specimen without being affected by the amt. of intact β2 glycoprotein which is considered to be contained in the specimen, and a monoclonal antibody used therein. ;SOLUTION: A first monoclonal antibody is not reacted with β2 glycoprotein I but is reacted with β2 glycoprotein I partially receiving cleavage by protease, and a second monoclonal antibody is reacted with β2 glycoprotein I and β2 glycoprotein I partially receiving cleavage by protease. In this immunological analysis, at least one first monoclonal antibody and a separate kind of the first monoclonal antibody or the second monoclonal antibody are used.;COPYRIGHT: (C)2000,JPO