PRODUCTION OF LAURYL LACTAM BY PHOTONITROSATION OF CYCLODODECANE AND BECKMANN REARRANGEMENT OF OXIME IN PRESENCE OF METHANE SULFONIC ACID

摘要

PROBLEM TO BE SOLVED: To produce lauryl lactam in a high yield without releasing sulfur dioxide and without hydrolyzing a part of the oxime and the lactam by the photonitrosation reaction of cyclododecane and the Beckmann rearrangement of the obtained oxime in the presence of methane sulfonic acid.;SOLUTION: This method for producing lauryl lactam comprises (A) subjecting cyclododecane, a nitrosation agent (for example, includes nitrosyl chloride and is preferably adjusted in a concentration of 0.1-25 g/L) and hydrogen chloride (excessively introduced in the form of anhydrous gas in an excessive amount based on the nitrosation agent) in an organic solvent to a photochemical reaction (the irradiation is carried out using a mercury or sodium lamp emitting light having wavelengths of usually 500-700 nm, preferably 565-620 nm, preferably at -20 to 40°C under vigorous stirring) to produce cyclododecane oxime, and subsequently (B) subjecting the obtained oxime to a Beckmann rearrangement reaction (generally at 120 to 180°C for 2 min to 1 hr under vigorous stirring).;COPYRIGHT: (C)2000,JPO