首页> 外国专利> Use of compounds capable of displacing the CIS - N - cyclohexyl Ethyl N - 3 - (3-chloro-4 Ciclohexilfenil) Allyl Amine tritiated of their Receptors, unaamina,A process for preparing such a compound usable Amine, Amine and in the preparation of such a Pharmaceutical composition

Use of compounds capable of displacing the CIS - N - cyclohexyl Ethyl N - 3 - (3-chloro-4 Ciclohexilfenil) Allyl Amine tritiated of their Receptors, unaamina,A process for preparing such a compound usable Amine, Amine and in the preparation of such a Pharmaceutical composition

机译:能够取代其受体的CIS-N-环己基乙基N-[3--(3-氯-4环己基芬太尼)烯丙基胺)的化合物的使用,一种制备这种化合物的方法,可使用胺,胺和这种药物组合物的制备

摘要

3. Pretreatment of anti-proliferation drug synthesis with tributylamine which can remove CIS N-cyclohexyl N-ethyl - [3 - (3-chloro-4-cyclohexane) propylamide] from its receptor. The invention also relates to an amine selected from these compounds, a procedure for preparing the amine, a compound which can be used for preparing the amine and a pharmaceutical compound containing the amine. It was found that the compound, Sr 31747, can prevent the proliferation of carcinogenic cells, so it can carry out anti-tumor activities;They also have access to these cells
机译:3.用三丁胺预处理抗增殖药物的合成,该三丁胺可从其受体中除去CIS N-环己基N-乙基-[3-(3-氯-4-环己烷)丙基酰胺]。本发明还涉及选自这些化合物的胺,制备该胺的方法,可用于制备该胺的化合物以及含有该胺的药物化合物。发现该化合物Sr 31747可以阻止致癌细胞的增殖,因此可以进行抗肿瘤活性;它们还可以进入这些细胞

著录项

  • 公开/公告号AR008090A1

    专利类型

  • 公开/公告日1999-12-09

    原文格式PDF

  • 申请/专利权人 VANMECHELEN EUGEEN;

    申请/专利号AR1997P103405

  • 发明设计人

    申请日1997-07-28

  • 分类号C07D211/12;C07D295/06;A61K31;A61K31/13;A61K31/135;A61K31/137;A61K31/35;A61K31/40;A61K31/445;A61K31/4453;A61K31/4465;A61K31/451;A61K31/495;A61K31/535;A61K31/5375;A61K31/55;A61K51;A61P35;A61P35/02;A61P43;C07C209/04;C07C209/44;C07C209/60;C07C211/25;C07C211/27;C07C211/28;C07C211/29;C07C211/34;C07C211/40;C07C211/41;C07C211/52;C07C221;C07D211/14;C07D211/16;C07D211/18;C07D211/22;C07D211/52;C07D211/70;C07D221/20;C07D223/04;C07D225/02;C07D241/04;C07D295/073;C07D307/33;

  • 国家 AR

  • 入库时间 2022-08-22 01:57:33

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