Derivatives of N - aryl methylamino replaced the ciclobuten - 3.4 - dionas, a Pharmaceutical composition containing them and the use thereof in lapreparacion a Medicine.

摘要

Described Derivatives of N - aryl methylamino replaced the ciclobuten - 3.4 - dionas of formula (i), wherein R1 is a straight chain Alkyl of 1 to 10 carbon ATOMS,Branched chain Alkyl 3 to 10 carbon ATOMS, cycloalkyl 3 to 10 carbon ATOMS, hidroxialquilo 2 to 10 carbon ATOMS,Fluoroalquilo 1 to 10 carbon Atoms or polifluoroalquilo 1 to 10 carbon Atoms; R2 and R3 are independentlyHydrogen or unsustituyente acyl group which is selected by the Formilo, alcanoilo 2 to 7 carbon ATOMS, alquenoilo 3 to 7 carbon ATOMS,Alcoxicarbonilo straight chain of 2 to 12 carbon ATOMS, alcoxicarbonilo branched chain of 4 to 10 carbon ATOMS, CIC loalcoxicarbonilo 4a 11 Carbon Atoms.Alquenoxicarbonilo 2 to 12 carbon ATOMS, aralcoxicarbonilo 6 to 12 carbon ATOMS, alquilsulfonilo 1 to 7u00e1tomos Carbon aroilo 7 to 12 carbon Atoms.Arilalquenoilo from 9 to 20 carbon ATOMS, arilsulfonilo 6 to 12 carbon Atoms.Arilalcanoilode 8 to 12 carbon Atoms or arilalquilsulfonilo 7 to 12 carbon ATOMS, with the proviso that when R3 is alcoxicarbonilo straight chain of 2 to 11u00e1tomos Deca rbono,Alcoxicarbonilo branched chain of 4 to 10 carbon ATOMS, cicloalcoxicarbonilo 4 to 11 Carbon Atoms.Alquenoxicarbonilode 2 to 11 Carbon Atoms or aralcoxicarbonilo 6 to 12 carbon ATOMS, R2 is Hydrogen; or a pharmaceutically acceptable Salt of the same.A Pharmaceutical composition containing aredescribed in the derivatives and the use thereof in the preparation of a Medicine.