Sulfonilaminocarboxilicos acids Compounds, Process for their preparation, Intermediates for their Exclusive use in these procedures, medicines,Process for the preparation of Medicines, use of these compounds for the preparation of medicines.

摘要

2. Thiohydrazide, which has the stereoisomerization form of type I and (or) a salt collection characteristic of type I compound and (or) is physiologically compatible, represents the copolymerization of ene La R2 and R3 with a carbon box group, and is at one end of part of type II formula; If R represents one of the carbon atoms in an integer of zero, 1, 2, or 3, and / or the ring, then - or--S- or - (R7) N-,R7 stands for (1) one hydrogen atom, 2) tar (C1-6),(3) Phenyl, phenyl refers to the phenyl which is not substituted for osusitude as described in 2.1 to 2.14, or (4) benzene, in which, benzene refers to the phenyl which is not substituted or not substituted as described in 2.1 to 2.14, or (5) r2n-c (= NH) - R2 has the above meaning, And / or the second part of the equation, the carbon atom in the ring is replaced by tar (C1-6) with multiple vezo particles once,Phenyl, phenyl - (CH2) M-ORepresents (1) one hydrogen atom, 2) tar (C1-6) -,(3) Ho-c (o) - tar (c21-6) - 4. Phenyl - (CH2) n -,The primary or secondary phenyl as described in 2.1 to 2.14 is not substituted or substituted, or with - nh-c (or) - Bitumen (c1-3) yn representing an integer of zero, 1 or 2, or 5) particles, or (6) R4 and R5 are formed, coupled with the amino group at elanillo, forming a ring of 4 to 7 rings, One of the carbon atoms was eventually replaced by - O --S-o-nh - or two adjacent C atoms, four to seven steps are part of a root base, (a) covalent bond, b) - orc) -CH 3DCH- o d) -C C-B a) - (CH2) m-M has the above elsign, b) - O - (CH2) P, where p is an integer from 1 to 5, or (c) - CH = ch - and x-ch = ch -.A sulfur oxygen atom