Plasmid, composition, process of immunizing an individual against a pathogen, recombinant vaccine, live attenuated pathogen, substantially pure bl-1 protein, recombinant expression vector, and isolated antibody

摘要

'' PLASMID, COMPOSITION, IMMUNIZATION PROCESS OF AN INDIVIDUAL AGAINST A PATHOGEN, RECOMBINANT VACCINE, ATTENTIONED LIVE PATHOGEN, SUBSTANTIALLY PURE PROTEIN, EXCELLENT VECTOR ISOLATED, 'EOL'. Enhanced vaccines are presented, which include a nucleotide sequence encoding IL-12, GM-CSF, IL-1, TNF- 244, TNF- 225, IL-2, IL-4, IL-5, IL -10, IL-15, IL-18 AND / OR BL-1 operably linked to regulatory elements. Enhanced vaccines include DNA vaccines, recombinant vaccines for foreign antigen release and live attenuated vaccines. Immunization processes of individuals are presented. Pharmaceutical compositions are presented comprising nucleic acid molecules that encode one or more immunomodulatory proteins selected from the group consisting of IL-12, GM-CSF, IL-1, TNF- 244, TNF- 225, IL-2, IL -4, IL-5, IL10, IL-15, IL-18 AND BL-1. An immunomodulatory protein, BL-1, and nucleic acid molecules that encode BL-1, are presented. Processes for producing and using BL-1 are presented.